Ulcers
Reduction of salivary gland secretion
Lichenoid reaction
Mucositis
Opportunistic infections
Hyperplasia
Ulcers
Medication such as aspirins and other NSAIDS if kept
prolonged in the mouth can cause caustic or chemical trauma
Management: education- inform patients on the danger of
administration of aspirin as lozenges
Chemotherapy drugs in the treatment of neoplastic lesion, not
necessarily in the mouth, may also cause ulcers of the oral mucosa. Such medications are:
Management: symptomatic to relieve the pain associated
with the pain by prescribing Difflam
(Benzydamine HCl 0.15%)
Reduction in salivary secretion
Main drugs that causes reduction in salivary secretions are:
Mono-Amine Oxidate Inhibitor (MAOI)
Tricylic anti-depressant
Chemotharapy
Management: Alternative medications which side effect in
terms of xerostomia to be discussed with medical practitioner, if conditions are found to
be unbearable. Alternative drugs to MAOI and Tricyclic antidepressant are SSRI's such
Fluoxetene, which has lower xerostomic effects.
In the event that the these medications cannot be compromised
such as chemotherapy for cancer treatment, and xerostomia is not tolerable , medication
such as sialogogues and artificial saliva can be utilised.
Lichenoid reactions:
Drugs such as Allopurinol for the treament of gout cause
these reactions. Management of such patients is reassurance and perhaps biopsy of
the area to discount more sinister causes.